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THE SCIENCE BEHIND THE MEAL

Better metabolic health starts with the meal.

What we eat matters. But how our food is broken down during digestion matters too.

Developed in Sweden through more than 15 years of research, SiPore® is a patented technology designed to work locally in the gut and slow the breakdown of carbohydrates and fats.

This is the science behind laga’s meal-level starting point.

Explore how it works
15+
years of research
6
clinical trials
9
peer-reviewed publications
10+
granted patents
HOW SIPORE® WORKS

A different way to work with the meal.

The carbohydrates and fats in food are broken down during digestion.

SiPore® introduces a different approach: working locally with the digestive process itself.

Start with your meal.

Digestive enzymes help break down carbohydrates and fats from the food you eat.

Entrap a portion of digestive enzymes.

SiPore®’s precisely engineered porous silica particles entrap a portion of enzymes such as amylase and lipase.

More gradual digestion.

With a portion of these enzymes entrapped, carbohydrates and fats break down more gradually, allowing energy from the meal to enter the system more gradually.

Sophisticated science.
A simple action at the meal.

Explore the full mechanism at SiPore.com
FEATURED CLINICAL RESEARCH

The SHINE Trial

A major milestone in the SiPore® research program.

SHINE was a 12-week, randomized, double-blind, placebo-controlled, multicenter clinical trial investigating engineered mesoporous silica particles in adults with overweight or obesity and prediabetes or newly diagnosed type 2 diabetes.

The study investigated glycaemic control and other measures of metabolic health.

The results were published in eClinicalMedicine, part of The Lancet Discovery Science.
Read the SHINE publication
318
participants
12
weeks
27
clinical sites
2026
publication
DESIGNED TO WORK LOCALLY

At the meal. In the gut.

SiPore® works locally in the gastrointestinal tract, where digestion takes place.

Its precisely engineered particles do not enter the bloodstream.

Works locally

SiPore® performs its function during digestion rather than acting systemically.

From the first meal

Its local mechanical mode of action begins during digestion of the first meal it is used with. No loading period is required for the mechanism to begin.

Studied in people

Safety and tolerability have been evaluated in the broader SiPore® human research program, where the technology has generally been well tolerated.

Explore safety and tolerability research

Read research
SCIENCE, BUILT INTO REAL LIFE

Science at the meal. Progress built around your life.

SiPore® gives laga a scientifically grounded starting point at the meal.

In the initial laga program, SiPore Liquid is the finished product used as the meal-level intervention.

From there, laga brings together personal health data, intelligent insights and human guidance to help you understand your starting point and identify what deserves attention next.

A simple action at the meal.
A broader approach built around you.

Start with laga Discovery.

Fourteen days to explore your metabolic-health patterns through the meals you eat and the life you live.

Start DiscoveryExplore the full science at SiPore.com
14 days · $149
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